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News
Cracking Code Of Gene Regulation
32+ min ago (394+ words) EPFL researchers help complete the largest map yet of how human cells read DNA and reveal how chemical marks can change the meaning of the genetic instructions. Every cell in the body contains essentially the same DNA; and yet, a…...
Patient-Focused Science Targets Rare Genetic Disorders
1+ hour, 53+ min ago (600+ words) Shannon Knight attributes her interest in neuroscience to an experience she had in high school. She and her sister attended a medical day for students at the nearby University of Illinois Chicago. As they were on their way out of…...
Tackling rare genetic disorders with patient-focused science
1+ hour, 56+ min ago (600+ words) Shannon Knight attributes her interest in neuroscience to an experience she had in high school. She and her sister attended a medical day for students at the nearby University of Illinois Chicago. As they were on their way out of…...
Rewriting Disease: Oligonucleotides Take Aim at the Untreatable
8+ hour, 38+ min ago (345+ words) How synthetic DNA and RNA are becoming the discovery engines behind a new generation of precision therapies By Mike May, PhD Oligonucleotides are engineered sequences of nucleic acids, typically ranging from 10 to 50 nucleotides in length. Because they can be designed…...
The Immortal Cells of Henrietta Lacks: A Story of Science, Legacy, and Ethics
8+ hour, 16+ min ago (619+ words) Henrietta Lacks In 1951, Henrietta Lacks, a 31-year old African-American woman, seeks treatment for cervical cancer at …...
Virus-like particles enable targeted gene engineering, pooled CRISPR
12+ hour, 20+ min ago (775+ words) Primary human myeloid cells are emerging as important components of next-generation immunotherapies, but they have traditionally been difficult to engineer at the scale and precision needed for modern functional genomics....
Running Paediatric Gene Therapy Studies: Operations and Oversight in Practice, Upcoming Webinar Hosted by Xtalks
1+ day, 26+ min ago (213+ words) This webinar provides a comprehensive overview of practical considerations for running paediatric gene therapy studies. Solomon Kamal-Uddin, Medical Advisor, and Lakshmi Guduri, Senior Director, Project Management at TFS HealthScience, have supported these programmes from start-up through long-term follow-up—Solomon from…...
Faulty gene copy can disrupt heart's 3D DNA structure, researchers find | The Business Guardian - newspaper - Read this story on Magzter.com
3+ day, 7+ hour ago (493+ words) The study, led by researchers at Gladstone Institutes and published in Science, found that the gene TBX5 plays a role not only in controlling gene activity but also in organising the genome's three-dimensional structure. When one copy of the gene is…...
Researchers say a faulty gene copy can make the heart's DNA fold wrong way
3+ day, 12+ hour ago (1090+ words) Washington DC: Researchers have discovered that a gene linked to congenital heart disease acts like an architect for the heart cell’s DNA. Losing just one copy of TBX5 can cause the genome’s carefully folded 3D structure to unravel, disrupting the genes needed to…...
TBX5 gene loss may disrupt DNA folding and trigger heart defects
3+ day, 10+ hour ago (28+ words) | Tap to know more | Inshorts Inshorts TBX5 gene loss may disrupt DNA folding and trigger heart defects...